Profuse Upper GI Bleeding Secondary to Eosinophilic Esophagitis

Non-variceal Upper Gi Bleeding

Introduction In the United States, there are 250,000-300,000 hospital admissions and 15,000-30,000 deaths each year resulting from acute non-variceal upper gastrointestinal bleeding NVUGIB.1 Peptic ulcer disease is the most prevalent source of NVUGIB accounting for 50% of all cases. The incidence of NVUGIB ranges from 48-160 cases per 100,000 adults yearly. Recent data suggest the mortality fro...

Management and Prevention of Upper GI Bleeding

1. Apply an understanding of the pathophysiology and risk factors for upper gastrointestinal (GI) bleeding to patient care. 2. Evaluate the most recent guidelines for management and prevention of upper GI bleeding. 3. Devise a plan to effectively manage acute GI bleeding and optimize treatment responses in the individual patient. 4. Design plans for the prevention of upper GI bleeding caused by...

Lymphocytic esophagitis mimicking eosinophilic esophagitis

A 74-year-old male with a history of dysphagia for 3 years presented with acute food impaction. Endoscopy showed a tight distal stricture with course rings at the middle third of the esophagus. Biopsies taken from the middle third of the esophagus showed marked infiltration of the intraepithelial lymphocytes mainly in a peripapillary distribution. The immunostains showed presence of CD3 and CD5...

Eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last decade. Diagnosis of the disorder is dependent on the patient's clinical manifestations and histologic findings on esophageal mucosal biopsies. Patients with eosinophilic esophagitis should be referred to both an allergist and gastroenterologist for optimal management, wh...

Eosinophilic esophagitis.